Probably every person has heard about how important is the immunity for normal functioning of all organs and systems of a human. It is precisely because of the activity of protective forces that our body can resist the attacks of viruses, infections, and other aggressive particles. Every year, many people turn to doctors with complaints of lowering their immunity and try to raise it with all their forces. However, sometimes the normal functioning of this system of the body can be harmful. In this case, doctors have to prescribe immunosuppressants – Prograf 0,5, Prograf 1. Let’s consider their effect, the scope of use, which benefits and harm to the body when they are consumed.
Immunosuppressants are a type of drugs that can suppress human immunity artificially. Often, such substances are used for surgical organ transplants, since they are able to prevent rejection of new tissues. In addition, immunosuppressants can become the drug of choice for autoimmune diseases.
The benefit of immunosuppressants for the human body
Immunosuppressants in the field of organ transplantation help to prevent rejection of foreign tissues. As practice shows, the use of such substances (accompanied by inhibition of lymphocyte activation) helps to extend the life of the transplanted organ.
In the treatment of an illness of the immune system, immunosuppressants help stop the pathological processes of some diseases (for example, rheumatoid arthritis, red lupus erythematosus, etc.) or assist to slow down their course.
The harm of immunosuppressants for the human body
Any medicine that has immunosuppressive properties can damage the body through a wide range of side effects. Especially a lot of them are in cytostatics. For example, azathioprine can provoke nausea, vomiting, loss of appetite, and so on. And in some cases, its consumption becomes the cause of the development of toxic hepatitis.
In addition, it should be noted that the use of immunosuppressive drugs is a natural suppression of immunity. Accordingly, patients undergoing treatment with immunosuppressive drugs are unstable to the action of pathogenic microorganisms and other aggressive substances, including those that are resistant to antibiotics. There is also evidence that immunosuppression may increase the likelihood of developing cancerous diseases by an order of magnitude.
These drugs include a number of static agents, they have a pronounced antiproliferative effect on cells, that is, it prevents their reproduction. Immunodepressants are classified in several varieties:
- those who completely suppress the immune response;
- have a specific impact;
- eliminate reactions accompanied by immune processes;
- with anti-inflammatory action.
There are special immunosuppressants, aimed at reducing the body’s defenses, they can cause inhibition of hematopoiesis, activation of secondary infection and other undesirable effects.
Immunosuppressants are a special group of drugs, they are very important and sometimes vital, but they should be used with caution, as they have a number of side effects.